JP JP2023116510A

Genetically modified immune cells containing microRNA-adapted SHRNA (SHRNAMIR)

Publication no.

JP2023116510A
Priority date
2019-04-03
Filing date
2023-05-24
Published
2023-08-22
Assignee
Precision Biosciences Inc
Inventor

マーティン，アーロン

Abstract

A genetically engineered immune cell comprising in its genome a nucleic acid sequence encoding a microRNA-compatible shRNA (shRNAmiR), wherein the shRNAmiR is expressed in the genetically engineered immune cell and the shRNAmiR is a target protein in the genetically engineered immune cell.

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