IN IN4054DEN2015A
A hand held pre filled syringe assembly comprises a syringe barrel a piston slidably located within the syringe barrel biasing means coupled to the piston and acting to bias the piston within the syringe barrel a hypodermic needle and an openable closure having an inlet and an outlet disposed between the syringe barrel and the hypodermic needle. The inlet of the openable closure is removably coupled to a nozzle of the syringe barrel by a first coupling and the outlet of the openable closure is coupled to a proximal end of the hypodermic needle by a second coupling. The openable closure defines a through channel extending between the inlet and the outlet that is closed by a normally closed valve. The syringe assembly contains a liquid medicament retained within the syringe barrel under pressure applied by the piston such that the liquid medicament is delivered through the hypodermic needle when the normally closed valve is opened.
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