EP EP4785963A1

MAGNETIC NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS

Publication no.

EP4785963A1
Priority date
2025-01-31
Filing date
2025-01-31
Published
2026-08-05
Assignee
INSTITUT QUIM DE SARRIA CETS FUNDACIO PRIVADA [ES], UNIV BOSTON [US], AORTYX [ES]
Inventors

RABADÀ SOLER YVETTE [ES], FORNAGUERA PUIGVERT CRISTINA [ES], MARTORELL JORDI [ES], WONG JOYCE Y [US], O SHEA TIMOTHY [ES], PARK IN YOUNG [US]

Abstract

[0001] The invention relates to a method of covalently attaching cationic polymers, including poly(beta-amino esters), to magnetic nanoparticles. The invention further relates to magnetic nanoparticles comprising cationic polymers covalently attached thereto, polyplexes comprising the magnetic nanoparticles, as well as use of these nanoparticles and polyplexes in delivering nucleic acids to a target tissue.

Classification

A61K47/59AI
A61K47/69AI
A61K9/51AI
C12N15/87AI
A61K47/59
A61K47/6923
A61K47/6929
A61K9/5115
C12N15/87
C12N15/88
H01F1/0054
B82Y25/00

Source documents

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