US US20260221263A1
The current document is directed to methods and systems that plan and provide cost-effective, time-efficient, and safe therapeutic treatments to patients by generating personalized treatment and therapy plans for patients, including transcranial direct current stimulation (“tDCS”) and transcranial magnetic stimulation (“TMS”). Currently disclosed implementations of these methods and systems incorporate whole-brain network models that are based, in part, on coupled differential equations. Model parameters are adjusted to simulate a patient's brain. Using results of a specified and generally limited number of treatment-application experiments, the currently disclosed methods and systems refine the whole-brain network model to accurately predict treatment efficacies in order to plan optimal or near-optimal treatments.
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