WO WO2026120611A1
The present disclosure relates to a microfluidic device (100) comprising a base member (110) defined with an inlet conduit (112) and an outlet conduit (114), a magnet (140) positioned below the base member (110) The base member (110) includes a plurality of microchannels (116) and is configured to trap a biological sample (200) bounded with silica-coated magnetite nanoparticles under the influence of magnetic field of the magnet (140). The base member (110) further includes a plurality of partition walls (118) defined with a plurality of microgrooves (118a) fluidly interconnecting the adjacent microchannels. The plurality of microgrooves (118a) is configured to selectively allow flow of the processed biological sample to the outlet conduit (114) of the device (100). The biological sample collected at the outlet (114b) exhibit a sorting efficiency of 81% for X sperm cells (200X) and 19% for Y sperm cells (200Y).
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