US US20260199573A1
On-site production of dialysate solution can be accomplished by mixing a base dialysate solution at a low concentration of dextrose with a concentrated dialysate solution at a high concentration of dextrose, allowing for weight savings when shipping dialysate solution to a patient. The base dialysate solution can be mixed in a large reservoir using purified water provided by a water purifier on-site, allowing for a small amount of dextrose or electrolytes to be mixed with the water to create tens of liters of dialysate solution. A peritoneal dialysis machine can be configured to mix the base dialysate solution from the reservoir with the concentrated dialysate solution to create, on-demand, a target dosage dialysate solution at any desired target concentration. The peritoneal dialysis machine can further be configured to heat the base dialysate solution to a sterilization temperature and direct the heated solution through the disposable cassette and external lines to sterilize the disposable set and enable reuse thereof.
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