IN IN790DELNP2012A

NOVEL FXR (NR1H4) BINDING AND ACTIVITY MODULATING COMPOUNDS

Publication no.

IN790DELNP2012A
Priority date
2009-08-19
Filing date
2012-01-27
Published
2015-06-26
Assignee
PHENEX PHARMACEUTICALS AG [DE]
Inventors

KREMOSER CLAUS [DE], ABEL ULRICH [DE], STEENECK CHRISTOPH [DE], KINZEL OLAF [DE]

Abstract

[0001] The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of the NR1H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds.

Classification

C07D249/06AI
A61K31/4192
A61K31/42
A61K31/422
A61K31/423
A61K31/4439
A61P1/00
A61P1/16
A61P13/12
A61P25/00
A61P25/02
A61P25/28

Source documents

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